By David Kerr, Annie Young, Richard Hobbs

ISBN-10: 0727915266

ISBN-13: 9780727915269

(BMJ Books) Univ. of Birmingham, united kingdom. Covers key components of sufferer care and offers debate round the quite a few uncertanties in regards to the affliction. colour illustrations. Softcover.

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Additional resources for FD Richard Hobbs, ABC of Colorectal Cancer

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Monoclonal antibodies directed against tumour antigens Monoclonal antibodies against tumour antigens have been shown to elicit immune responses against the tumour, which may previously have induced immunogenic tolerance. The 17-1A antigen is a surface glycoprotein with a putative role in cell adhesion and is present in over 90% of colorectal tumours. In a study among patients with Dukes’s stage C colon cancer the patients were randomised to receive either surgery alone or surgery plus repeat administrations of a monoclonal antibody against the 17-1A antigen.

Hospital or community coordination of follow up? Most patients with colorectal cancer are followed up in hospital. Yet overwhelming evidence from previous studies shows that few curable recurrences are detected at routine follow up based on history, physical examination, and routine blood tests. 3 Comparison of results of trial of early versus delayed chemotherapy in patients with advanced colorectal cancer Treatment group Early Delayed No of patients 92 91 Median symptomfree survival (months) 10 2 Median survival (months) 14 9 Survival at 1 year (%) 55 38 Early chemotherapy was given when patients were asymptomatic; delayed chemotherapy was given when patients were symptomatic.

X Parry JM, Collins S, Mathers J, Scott NA, Woodman CBJ. Influence of volume of work on the outcome of treatment for patients with colorectal cancer. Br J Surg 1998;86:475-81. x Porter GA, Soskolne CL, Yakimets WW, Newman SC. Surgeon-related factors and outcome in rectal cancer. Ann Surg 1998;227:157-67. 3 Outcome seems to differ substantially among surgeons performing colorectal surgery—specialisation rather than volume of work might be a way of improving overall outcome 21 7 Adjuvant therapy Rachel S J Midgley, D J Kerr Despite substantial improvements in surgical technique and postoperative care, colorectal cancer continues to kill 95 000 people in Europe alone each year.

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FD Richard Hobbs, ABC of Colorectal Cancer by David Kerr, Annie Young, Richard Hobbs


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