By C. J. Parker (auth.), Charles J. Parker A. B., M.D. (eds.)

ISBN-10: 3642770142

ISBN-13: 9783642770142

ISBN-10: 3642770169

ISBN-13: 9783642770166

In this quantity a entire overview of membrane proteins that keep an eye on supplement and perforin-mediated cytolysis is gifted. a close analysisis supplied of the biochemical, molecular, and practical positive aspects of those proteins; the glycosyl phosphatidylinositol associated proteins are coated, with emphasis put on the sensible value of this sort of membrane anchor. additional chapters contain reports of the consequences of supplement activation on cells which are metabolically energetic, and of the legislation of cellphone killing through cytotoxic lymphocytes, contemplating the similarities and disparities among the supplement and perforin platforms. The healing use of recombinant CR1 for immune-mediated pathophysiological tactics is mentioned in a separate section.

Show description

Read Online or Download Membrane Defenses Against Attack by Complement and Perforins PDF

Similar nonfiction_8 books

Ordering at Surfaces and Interfaces: Proceedings of the - download pdf or read online

This quantity includes the complaints of the 3rd in a sequence of biennial NEC Symposia on basic ways to New fabric stages subsidized via the NEC company, Tokyo, Japan. The symposium used to be held from October 7 to eleven, 1990, on the Hakone Kanko H9tel in Hakone. approximately forty invited members stayed jointly, grew to become serious about excessive discussions, and freely exchanged principles either out and in of the convention room, which confronted Mt.

Get Large Clusters of Atoms and Molecules PDF

Very lately it has develop into attainable to supply and symbolize huge clusters containing a precise, predetermined variety of atoms. via those efforts it has turn into transparent that clusters containing while many as 20,000 atoms can't but be regarded as being tiny crystals. Their constitution is frequently icosahedral.

Get Biophysical approaches to translational control of gene PDF

This e-book presents a ultimate source on figuring out the ribosome's crucial nature and the way it interacts with different proteins and nucleic acids to regulate protein synthesis. As one of many valuable foundations in our figuring out of the biology on the molecular point, this subject appeals to a large viewers, from bench researcher to clinician.

Cellular and Molecular Mechanisms in Hypertension - download pdf or read online

High blood pressure is well-known to be one of many significant chance components for the improvement of peripheral vascular affliction. the decade has witnessed a number of significant advances in remedy for high blood pressure, together with the advance of angiotensin-converting enzyme inhibitors and calcium channel blockers. those compounds have drastically better the facility to regulate blood strain and to lessen the impression of this threat issue on morbidity and mortality.

Extra info for Membrane Defenses Against Attack by Complement and Perforins

Example text

The LHRs of the A allotype have been designated A, B, C, and D types, whereas the fifth LHR of the B allotype is designated A/B because of its sequence similarity to both the A and B LHR. The C3b and C4b binding domains of CR1 have been localized to the terminal three LHR (A, B, and C) of the A allotype. These studies were facilitated by the positioning of convenient restriction sites at the boundaries of each LHR. This allowed recombinant CR1 to be investigated by selectively deleting one or more of the LHRs (KLICKSTEIN et al.

Immunol Today 7: 230-234 Rey-Campos J, Rubinstein P, Rodriguez de Cordoba S (1987) Decay-accelerating factor. Genetic polymorphism and linkage to the RCA (regulator of complement activation) gene cluster in humans. J Exp Med 166: 246-252 Rhee SG, Suh PG, Ryu SH, Lee SY (1989) Studies of inositol phospholipid-specific phospholipase C. Science 244: 546-550 Rimoldi MT, Sher A, Heiny S, Lituchy A, Hammer CH, Joiner K (1988) Developmentally regulated expression by Trypanosoma cruz; of molecules that accelerate the decay of complement C3 convertases.

Proc Nail Acad Sci USA 80: 5430-5434 Pearce EJ, Hall BF, Sher A (1990) Host-specific evasion of the alternative complement pathway by schistosomes correlates with the presence of a phospholipase C- sensitive surface molecule resembling human decay accelerating factor. J Immunol144: 2751-2756 Perkins SJ, Haris PI, Sim RB, Chapman 0 (1988) A study of the structure of human complement component factor H by Fourier transform infrared spectroscopy and secondary structure averaging methods. Biochemistry 27: 4004-4012 Post TW, Arce MA, Liszewski MK, Thompson ES, Atkinson JP, Lublin OM (1990) Structure of the gene for human complement protein decay accelerating factor.

Download PDF sample

Membrane Defenses Against Attack by Complement and Perforins by C. J. Parker (auth.), Charles J. Parker A. B., M.D. (eds.)

by James

Rated 4.46 of 5 – based on 35 votes